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Mock Paper - Medical PG Entrace by Dr Chaudhry : Paschim Vihar, New Delhi 110063 T: 1142316457, 9810571993
A fresh Mock Paper is generated every time you open this page and every time you refresh it.For each of the following multiple choice questions, choose the most appropriate answer :
Anatomy
1. In walking, the hip bone of the suspended leg is raised by which of the following muscles acting on the supported side of the body?
A. Gluteus maximus
B. Gluteus medius
C. Obturator internus
D. Quadratus femoris
2. Ansa cervicalis innervates which muscle
A. mylohyoid
B. cricothyroid
C. stylohyoid
D. sternohyoid
3. All is true about development & maturation of sperms except
A. Primordial germ cells are dormant till puberty
B. Spermatogonium becomes mature sperm in 74 days
C. Progressive motility is gained in the epididymis
D. Stored in the seminal vesicle before ejaculation
4. De Quervain's disease classically affects
A. Flexor pollids longus and brevis
B. Extensor carpi radialis and extensor pollicis longus
C. Abductor pollicis longus and brevis
D. Extensor pollicis brevis and abductor pollicis longus
5. Triangle Of Koch represents
A. S.A node
B. Septa! site of A.V node and associated juxtaglomerular bundles
C. Site of coronary occlusion
D. None of these
6. Non-spiral course of conotruncal septum gives rise to
A. Tetrology of Fallot
B. Patent truncus arteriosus
C. Transposition of great vessels
D. Coarctation of aorta
7. A 52-year-old woman was admitted to the hospital with a diagnosis of right-sided pleurisy with pneumonia. It was decided to remove a sample of pleural fluid from her pleural cavity. The resident inserted the needle close to the lower border of the eighth rib in the anterior axillary line. The next morning he was surprised to hear that the patient had complained of altered skin sensation extending from the point where the needle was inserted downward and forward to the midline of the abdominal wall above the
A. The needle was inserted too low down in the intercostal space
B. The needle was inserted too close to the lower border of the eighth rib and damaged the eighth intercostal nerve
C. The needle had impaled the eighth rib
D. The needle had penetrated too deeply and pierced the lung
8. Following structures pass posterior to the flexor retinaculum except :
A. Flexor digitorum superficialis tendons
B. Median nerve
C. Ulnar nerve
D. Flexor pollicis longus tendon
9. An 83-year-old man has trouble walking. At his physician’s office, he is asked to stand on his right foot and his left hip drops. Which of the following nerves is most likely damaged, causing his problem
A. Left inferior gluteal
B. Left superior gluteal
C. Right inferior gluteal
D. Right superior gluteal
10. All is true about Trochlear nerve except
A. Longest intracranial course
B. Arise from dorsal aspect
C. Supplies ipsilateral superior oblique
D. Arises from out side the common tendinous ring
Physiology
11. Impedance matching is a function of:
A. scala media
B. endolymph
C. ear ossicles and tympanic membrane
D. cochlear nucleus
12. Most of the calcium in the endoplasmic reticulum is sequestered by:
A. calmodulin
B. caldesmin
C. calsedulin
D. calsequestrin
13. Histamine released from mast cells in the stomach stimulates the secretion of HCl by parietal cells. What type of signaling is this?
A. Endocrine
B. Paracrine
C. Autocrine
D. Juxtacrine
14. Which of the following transporters is present only in the sinusoidal membrane of hepatocytes?
A. Bile Salt Export Pump
B. LDL-cholesterol receptors
C. MDR 3 (Flippase)
D. Multidrug Resistance associated Protein - 2 (MRP-2)
15. The calcium-binding protein that plays a key role in the regulation of smooth muscle cell contraction is:
A. dystrophin
B. calmodulin
C. troponin C
D. calcineurin
16. Which of the following types of cells work as scavenger cells in the CNS?
A. Microglia
B. Oligodendroglia
C. Ependymal cells
D. Astrocytes
17. Which of the following statements about CCK is incorrect?
A. It causes gall bladder contraction.
B. It relaxes the sphincter of Oddi.
C. It relaxes the pyloric sphincter.
D. It stimulates the secretion of an enzyme-rich pancreatic juice.
18. The major trophic hormone for Sertoli cells and the major stimulator of aromatase activity of Sertoli cells is:
A. inhibin
B. LH
C. FSH
D. Melatonin
19. Type I skeletal muscle fibers:
A. are called slow, oxidative fibers.
B. are innervated by slow motor units.
C. have slow myosin ATPase activity.
D. All these
20. The dense layer of collagen fibers that surround an entire skeletal muscle is the
A. Tendon.
B. Epimysium.
C. Endomysium.
D. Perimysium.
Biochemistry
21. Which of the following mineral is involved in protein metabolism and oxidation reactions?
A. Molybdenum
B. Manganese
C. Magnesium
D. calcium
22. Lack of reaction to our own human leukocyte antigens (HLAs) is known as?
A. autoimmunity
B. complement system
C. clonal selection
D. tolerance
23. Which of the following chemical reaction is involved in the production of GABA from glutamate?
A. Deamination
B. Decarboxylation
C. Oxidative decarboxylation
D. Transamination
24. Fructose is metabolized by
A. fructose 1-phosphate pathway
B. fructose 6-phosphate pathway
C. glyceraldehyde 3-phosphate pathway
D. both (a) and (b)
25. Which of the following (s) is/are serine proteases?
A. Chymotrypsin
B. Trypsin
C. Elastase
D. all of these
26. Agarose gel electrophoresis and pulsed field gel electrophoresis may be used to resolve respectively
A. 2000 kb and 20kb DNA
B. 1000 kb and l0kb DNA
C. 20 kb and 2000 kb DNA
D. 10 kb and 1000 kb DNA
27. In ion-exchange chromatography
A. proteins are separated on the basis of their net charge
B. proteins are separated on the basis of their size
C. proteins are separated on the basis of their shape
D. either (b) or (c)
28. Which of the following indicates that the pK of an acid is numerically equal to the pH of the solution when the molar concentration of the acid and its conjugate base are equal?
A. Michaelis-Menten equation
B. Haldanes equation
C. Henderson-Hasselbalch equation
D. Hardy-Windberg law
29. Where in a eukaryotic cell, DNA can be found?
A. Nucleus
B. Mitochondrion
C. Vacuole
D. Both (a) and (b)
30. In reverse phase chromatography, the stationary phase is made
A. non-polar
B. polar
C. either non-polar or polar
D. none of these
Pathology
31. Embryonic haemoglobin is composed up of :
A. Alpha and beta
B. Epsilon and gamma
C. Gamma and beta
D. Zeta and epsilon
32. Ihe commonest site of syphilitic aneurysm is :
A. Aorta
B. Median artery
C. Facial artery
D. Pulmonary artery
33. The virulence of Mycobacterium Tuberculosis is related to:
A. the production of exotoxin
B. the production of endotoxin
C. its ability to induce delayed type hypersensitivity
D. its ability to escape killing by polymorphonuclear phagocytes
34. The kidneys show acute cortical parenchymatous degeneration and necrosis of tubules. The kidneys are enlarged, cortex is swollen, pale, and oedematous in contrast to congested
A. Acute glomerulonephritis
B. Acute pyelonephritis
C. Acute renal failure
D. Shock kidney
35. Thalassaemia majar manifests in :
A. Childhood
B. Puberty
C. Adolescence
D. Middle age
36. Most common mechanism of GERDA.
A. Transient decrease in pressure at LES
B. Hypotension at lower esophageal sphincter
C. Hiatus Hernia
D. Gastritis
37. Brown induration is a type of chronic venous congestion occuring in :
A. Liver
B. Heart
C. Lung
D. Kidney
38. Leukocyte adhesion with transmigration involves all of the following EXCEPT
A. migration of leukocytes as a result of stasis of blood flow in the microvasculature.
B. interaction of integrins with immunoglobulin found on endothelial cells.
C. the selectins found only on endothelial cells.
D. ICAM-1 and VCAM-1 adhesive molecules on the endothelial cells
39. The causative organism of gas gangrene is :
A. Staphylococcus
B. Streptococcus
C. Leptospira
D. None of these
40. Calcification of media is most related to :
A. Atherosclerosis
B. Monckeberg's sclerosis
C. Diffuse arteriolar sclerosis
D. Thrombotic sclerosis
Microbiology
41. The time required to kill 90% of the microorganisms in a sample at a specific temperature is the
A. decimal reduction time
B. thermal death point
C. F value
D. D value
42. Gram staining was introduced by
A. Christian gram
B. Alfred Gram
C. Robertcook
D. Louis Pasteur
43. The five-kingdom system of classification was set up by
A. Louis Pasteur
B. Robert Whittaker
C. Robert Koch
D. Masaki Ogata
44. Which of the following is an abiotic elicitors?
A. UV irradiation
B. Osmotic shock
C. Heavy metal ions
D. All of these
45. The causative organism for AIDS was identified in the year
A. 1983
B. 1976
C. 1994
D. 1969
46. An elderly male presents 2 months after renal transplantation with nephropathy. Which of the following can be a viral etiological agent?
A. Polyoma virus BK
B. Human herpes virus type 6
C. Hepatitis C
D. Human papilloma virus, high risk types
47. Which of the following is responsible for a musty or earthy flavor?
A. Actinomycetes
B. Flavobacterium
C. both A and
D.
48. Antibodies to which of the following antigens of Bacillus anthracis are protective?
A. Capsular polypeptide
B. Somatic polysaccharide
C. Anthrax toxin
D. None of these
49. A patient has Bilirubin =0.9 mg/dl, elevated SGPT & SGOT (rv1500-1600 IU/L). HBsAg positive, Anti HBC IgM negative, Anti Hepatitis E IgM positive. Patient has
A. Chronic Hepatitis B infection with Hepatitis E superinfection
B. Hepatitis E Infection
C. Co-infection with Hepatitis B & Hepatitis E
D. Infection with mutant Hepatitis B virus
50. The ability of B. coagulans to grow in tomato juice depends upon the
A. number of spores present
B. the availability of oxygen
C. the pH of the juice
D. all of these
Pharmacology
51. The principal action of papaverine is :
A. Relief from pain
B. Antitussive
C. Vasodilation
D. Antiemetic
52. Procaine has all of the following properties EXCEPT:
A. It has ester linkage
B. Its metabolic product can inhibit the action of sulfonamides
C. It readily penetrates the skin and mucosa
D. It is relatively short-acting
53. Ganglion blocking drugs are used for the following emergencies EXCEPT:
A. Hypertensive crises
B. Controlled hypotension
C. Cardiovascular collapse
D. Pulmonary edema
54. Which of the following routers of administration is the most convenient, although may have a bioavailability anywhere from 5-100%?
A. PO (oral)
B. IV (intravenous)
C. IM (intramuscular)
D. SQ (subcutaneous)
55. Nonpharmacological pain relief treatments use the
A. Pain Oppression theory.
B. Pain Suppression theory.
C. Brain Suppression theory.
D. Gate Control theory
56. Which of the following is increased in intracellular concentration due to second messengers such as IP3?
A. K+
B. Ca++
C. Cl-
D. Na+
57. What type of study for an IND involves comparison with a placebo and another previously tested drug?
A. Single-blind study
B. Double-blind study
C. Placebo (negative-control)
D. Positive-control
58. What term is used to describe a more gradual decrease in responsiveness to a drug, taking days or weeks to develop?
A. Refractoriness
B. Cumulative effect
C. Tolerance
D. Tachyphylaxis
59. All of the following statements regarding diuretics are true EXCEPT:
A. Furosemide (Lasix) can increase the likelihood of digitalis toxicity
B. Chlorthalidone (Hygroton) can decrease the excretion of lithium
C. Ibuprofen can increase the antihypertensive effect of chlorthalidone
D. Chlorthalidone has a longer duration of action than furosemide
60. Main contraindications of estrogens’ therapy include the following:
A. Estrogen-dependent neoplasmas such as carcinoma of the endometrium or carcinoma of the breast
B. Undiagnosed genital bleeding
C. Liver disease
D. All of these
Forensic medicine
61. In oath-taking the witness has to keep hislher hand on a holy book
A. A medical man
B. A lawyer
C. An athiest
D. A magistrate
62. Thanatology is the science that deals with
A. Heinous crimes
B. Effect of metals on body
C. Psychiatric influences over body
D. Death
63. Hatter’s shakes are seen in which poisoning –
A. Mercury
B. Arsenic
C. Lead
D. Copper
64. A child is burnt by hot water, the best method to calculate the surface area of the burnt areas is:
A. Palm method
B. Lund and browder method
C. Rule of 9
D. Brocas method
65. A person was found dead with bluish green frothy discharge at the angle of mouth and nostrils. What is the diagnosis?
A. Arsenic poisoning
B. Copper poisoning
C. Mercury poisoning
D. Lead poisoning
66. In severe burns, the remanent indicative of male sex is
A. Penis
B. Testicle
C. Inguinal canal
D. Prostate gland
67. Antemortem drowning is diagnosed by
A. Weeds and grass in hand,
B. water in stomach,
C. Fine froth at mouth and nostrils,
D. Cutis Anserina,
68. A 7 year presented with intermittent abdominal cramps, loose stool and on stool examination ova of size 100 micrometre is seen. Which is not the cause?
A. Gastrodiscoides hominis
B. Fasciola gigantic
C. Echinostorum ileocaxnum
D. Opisthorcis viverrani
69. All are correct regarding Widal test, except –
A. Baseline titres differ depending on the endemicity of the disease
B. High titre value in a single widal test is not confirmative
C. H antibody cannot differentiate between types
D. O antibody lasts longer and hence is not indicative of recent infection
70. Cadaveric lividity differs from post-mortem staining in that :
A. It occurs only in the dependant parts
B. It occurs only upto 3-4 hours after death
C. It occurs only when death is caused by circulatory collapse
D. None of these